[HTML][HTML] Construction of an infectious bronchitis virus vaccine strain carrying chimeric S1 gene of a virulent isolate and its pathogenicity analysis

C Lv, T Shi, P Zhu, X Peng, S Cao, Y Yan… - Applied Microbiology …, 2020 - Springer
… in which S1 gene of IBV H120 was replaced with that of straingenetics established in this
study, recombinant H120 (rH120) strain and its chimeric virus rH120/SCS1 carrying S1 gene of …

Recombinant infectious bronchitis coronavirus H120 with the spike protein S1 gene of the nephropathogenic IBYZ strain remains attenuated but induces protective …

Y Jiang, X Cheng, X Zhao, Y Yu, M Gao, S Zhou - Vaccine, 2020 - Elsevier
… biological characteristics of the recombinant virus remained … The causative agent of IB is
infectious bronchitis virus (IBV), … the recombinant strain, rH120-S1/YZ, expressed the S1 gene

[HTML][HTML] Genetic and pathogenic characterization of a novel recombinant avian infectious bronchitis virus derived from GI-1, GI-13, GI-28, and GI-19 strains in …

W Yan, R Qiu, F Wang, X Fu, H Li, P Cui, Y Zhai, C Li… - Poultry Science, 2021 - Elsevier
… The ecto-domain region of the S2 subunit contains a fusion peptide … recombinant strain
originating from H120, 4/91, LDT3-A and LJL/08-1 strains, all of which are prevalent in the region. …

[HTML][HTML] Design and characterization of a DNA vaccine based on spike with consensus nucleotide sequence against infectious bronchitis virus

L Zuo, W Yan, Z Song, H Li, X Xie, K Gu, P Ma, Y Tian… - Vaccines, 2021 - mdpi.com
… With this in mind, the ectodomain of the consensus spike … IBV strain M41 as efficiently as its
homologous vaccine H120 (… IBV GI-1 strain in the virus challenge, however, more strains in …

Recombinant infectious bronchitis viruses expressing heterologous S1 subunits: potential for a new generation of vaccines that replicate in Vero cells

E Bickerton, G Dowgier… - Journal of General …, 2018 - microbiologyresearch.org
S1 subunit is derived from the IBV vaccine strain, H120, or the … ; replacement of the
ectodomain of the IBV Beaudette S … The growth characteristics of the P3-CKC and P7- or P11-…

Prevention and pathogenesis of avian infectious bronchitis: the role of infectious bronchitis virus spike proteins in cell attachment and protective immunity

FE Eldemery - 2017 - search.proquest.com
… We demonstrated that extension of S1 with the S2 ectodomainRecombinant avian infectious
bronchitis virus expressing a … IBV Beaudette strain S1 gene with that from the H120 strain

[HTML][HTML] Establishment and cross-protection efficacy of a recombinant avian gammacoronavirus infectious bronchitis virus harboring a chimeric S1 subunit

X Ting, C Xiang, DX Liu, R Chen - Frontiers in Microbiology, 2022 - frontiersin.org
… In this study, the rescued rIBV-Beau-KC(S1) strain with two … Recombinant IBVs expressing
heterologous S proteins have … S1 region) gene derived from either H120, M41, 4/91, or QX, …

The establishment and characteristics of cell-adapted IBV strain H120

Y Zhou, X Yang, H Wang, F Zeng, Z Zhang, A Zhang… - Archives of …, 2016 - Springer
… This means that producing infectious bronchitis virus vaccines always involves the … -R but
expressing the ectodomain region of the S1 gene of the H120 strain, and this recombinant IBVs …

[HTML][HTML] A reverse genetics system for avian coronavirus infectious bronchitis virus based on targeted RNA recombination

SJ van Beurden, AJ Berends, A Krämer-Kühl… - Virology journal, 2017 - Springer
… We established a reverse genetics system for the IBV strain H52… Another 68 passages resulted
in the IBV strain H120, which … the near full length ectodomain of the spike gene, 3211 nt in …

S2′ cleavage site plays a decisive role in expansion of Vero cell tropism by infectious bronchitis virus HV80, with Q855H promoting cell-to-cell fusion

Y Jiang, X Cheng, M Gao, X Dou, Y Yu, H Shen… - bioRxiv, 2023 - biorxiv.org
recombinants that expressed chimeric S glycoprotein, S1 or S2 subunit of strain H120, and
… (B) The structure prediction of the monomer of HV80 spike ectodomain in the prefusion …